Anterior
Also known as: Co:Helm, Florence
Clinical AI for health plans: the Florence system runs prior authorization and other plan workflows as background agents, completing cases where criteria are clearly met and escalating the rest to clinicians, with an immutable ledger of every action.
Anterior builds Florence, an AI system for regulated clinical work at health plans and their delegated partners, covering utilization management, HEDIS gap closure, payment integrity, risk adjustment, policy management and appeals. Florence ingests X12 EDI, HL7 v2, C-CDA, NCPDP, SFTP extracts and faxes, normalizes them to FHIR, and reasons across charts, feeds and the plan's policy text. In prior authorization it moves a case from intake through identification, validation, eligibility and network checks and guideline selection to a decision, completing automatically only where criteria are clearly met and otherwise escalating to a qualified human with a sourced evidence packet.
Every action is written to an immutable ledger with the reasoning and evidence behind each outcome, and deployments are evaluated on synthetic data before they go live, with feedback from LLM checks and human review in production. Anterior sells through programs (a Triage consultation, a Flow rollout for clinical review, Relay workflow automation and Steward) delivered with forward deployed clinicians, runs standalone or embedded in plan systems, and states SOC 2 Type II, HITRUST e1 and HIPAA compliance.
Vendor details
Canonical URL
https://www.anterior.com
Category
Healthcare agent
Funding status
$64M total; $40M round Feb 2026 (Sequoia, NEA, FPV, Kinnevik)
Company status
independent
Use cases & customers
Primary use cases
Target customers
Deployment options
Integrations
Ingests X12 EDI, HL7 v2, C-CDA, NCPDP, SFTP extracts, proprietary feeds and faxes, normalizes to FHIR, and writes outcomes back to plan systems and PAS responses to the EHR; states documented SDKs and APIs, with no reference linked.
In practice
A provider submits a prior authorization by portal or fax, and Florence takes it from intake through eligibility and network checks to a decision, completing it automatically when the criteria are clearly met.
A case that does not clearly meet criteria goes to a qualified clinician with a sourced evidence packet, and a plan that wants more caution runs Florence under human review so every outcome is checked before it commits.
A compliance team traces an authorization decision through the immutable ledger of events, from record access to final outcome, with the reasoning and evidence behind it.
Sources & related URLs
Agentic Index coverage score
8.5 / 14 capabilities · 61%
| Integrations & Tool Calling | Full |
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Data comes into Florence as X12 EDI, HL7 v2, C-CDA, NCPDP, SFTP extracts and faxes. Florence runs embedded in existing plan systems, and in the Relay case log it creates the authorization in the plan's system, verifies eligibility and network, and sends the PAS response bundle to the EHR. Anterior names the connected systems by standard, not by product. Sourceanterior.com/programs/relayread 2026-09-29 |
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| Workflow Orchestration | Full |
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Relay moves a case from intake to decision without handoffs, through intake, patient identification, validation, a duplicate check, authorization creation, eligibility and network checks, guideline selection and the decision. Each case passes a condition, completing automatically only where criteria are clearly met and escalating otherwise. Sourceanterior.com/programs/relayread 2026-09-29 |
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| Knowledge Grounding & RAG | Full |
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Florence normalizes inbound data to FHIR on ingestion and reasons across charts, faxes, structured feeds and the plan's policy text, selecting the applicable guideline and attaching the reasoning and supporting evidence to each outcome. Sourceanterior.com/florenceread 2026-09-29 |
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| Human Oversight & Guardrails | Full |
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Work completes automatically only where criteria are clearly met. Otherwise Florence escalates to a qualified person with a sourced evidence packet, and the plan can run Florence under human review instead of autonomously, so a person reviews the outcome before it commits. Sourceanterior.com/florenceread 2026-09-29 |
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| Security, Identity & Governance | Partial |
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Stated compliance covers SOC 2 Type II, HITRUST e1 and HIPAA, with audit trails, and a trust center is published at trust.anterior.com. There is no SSO, roles or other access model for customers. Sourceanterior.comread 2026-09-29 |
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| Observability & Auditability | Full |
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Every action, from record access through final outcome, is written to an immutable ledger of events, and each outcome carries the reasoning and supporting evidence behind it. Sourceanterior.com/florenceread 2026-09-29 |
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| Memory & State Persistence | Not documented |
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There is no memory layer with a scope or lifetime. Templates tuned with Anterior's clinicians are settings, and case data normalized to FHIR is the plan's record. Sourceanterior.com/programs/flowread 2026-09-29 |
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| Deployment & Data Residency | Not documented |
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There is no customer environment or hosting region. Interface components run standalone or embedded in plan systems, which is where the interface sits, not where data is hosted, and the privacy policy names no region and says providers may operate in the US and other countries. Sourceanterior.com/privacyread 2026-09-29 |
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| Prebuilt Agents, Templates & Packs | Partial |
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Florence is sold through four programs across plan functions. Triage is a consultation, Flow a rollout lasting weeks and Relay workflow automation, and the fourth is Steward. Flow's note templates are tuned with Anterior's clinicians. These are engagements and settings inside one system, not agents a customer can adopt separately. Sourceanterior.com/programs/triageread 2026-09-29 |
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| Triggers & Channel Coverage | Full |
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Florence runs as autonomous background agents on requests arriving through portal intake, EDI feeds, SFTP extracts and faxes, so a provider's submission starts the case with no one at the plan initiating it. Sourceanterior.com/florenceread 2026-09-29 |
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| Model Flexibility & Routing | Not documented |
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Florence is built on frontier models Anterior does not name, and customers cannot choose the model. Sourceanterior.comread 2026-09-29 |
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| APIs, SDKs & MCP Extensibility | Partial |
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Anterior states that documented SDKs and APIs expose its production capabilities for common plan systems, with clear contracts for production traffic. No reference, portal or access path is linked from its pages. Sourceanterior.com/programs/relayread 2026-09-29 |
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| Testing, Debugging & Optimization | Full |
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Synthetic data and evaluation at large scale catch issues before a deployment goes live, and in production, feedback from LLM checks and human review flows back so Florence improves case by case. This evaluates the plan's own deployment before and after release, and Anterior runs it, not the plan. Sourceanterior.com/programs/flowread 2026-09-29 |
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| Browser & Computer Use | Not documented |
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Florence works through data feeds, faxes and plan system integrations, and does not control a browser, desktop or computer. Sourceanterior.com/florenceread 2026-09-29 |
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The Agentic Index coverage score grades every vendor Full, Partial or Not documented against the same 14 buyer facing capabilities, from public evidence only. Each capability links to how all vendors in the index score on it. How this evidence is graded
Pricing
Contact sales; no pricing published
Not published.
What is public
No pricing is published on anterior.com; engagements start with a conversation with the team.
Variable cost rationale
No public rate or model on the vendor's site; cost likely scales with authorization volume and the plan functions covered (inference, not stated by the vendor).
Sales call required
Yes, required for paid access
Free / trial
No free tier or trial published.
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Alternatives to Anterior
The closest documented capability profiles to Anterior among healthcare agents tracked by Agentic Index, ordered by similarity on the same 14 point evidence the rankings use. No vendor pays for placement.
- Charta Health7.5 / 14A lighter documented profile than Anterior
- Nym7.5 / 14A lighter documented profile than Anterior
- Ember Copilot9.0 / 14Fuller documented coverage on Security, Identity & Governance and Prebuilt Agents, Templates & Packs
- RapidClaims8.0 / 14Fuller documented coverage on Prebuilt Agents, Templates & Packs
- CodaMetrix6.5 / 14A lighter documented profile than Anterior
- Cohere Health10.5 / 14Adds documented Deployment & Data ResidencyAnterior vs Cohere Health →
Similarity is computed from each vendor's Agentic Index coverage score evidence, axis by axis, not from the totals. How this evidence is graded