Agentic Index
Hyro vs Luma Health (2026)
Both run agent platforms for health system patient access at similar scale, 45 plus and 50 plus systems, documenting 8.5 and 8 of 14. That verdict is the Agentic Index coverage score, graded from each vendor's own published materials.
Hyro leads with the knowledge layer, a self updating knowledge graph resolving more than 85 percent of repetitive calls, chats and SMS, with responsible AI framing. Luma leads with orchestration, its Spark core coordinating named agents across access, intake, engagement and payments including a Navigator voice concierge, Document Flow and Order Management, with HITRUST r2 and SOC 2 Type II. Hyro answers questions better; Luma covers more of the journey and carries the stronger published certification posture.
On the Agentic Index healthcare agent ranking, Hyro clears the bar and Luma Health does not. Hyro documents all five chart loop capabilities in full; Luma Health documents two of the five in full. 8 of the 76 vendors in the lane clear it. See the healthcare agent ranking
This comparison is published by Agentic Index, an independent agentic AI vendor research platform. Hyro and Luma Health are each graded against the same 14 capability Agentic Index taxonomy, from the vendor's own public materials under the Agentic Index verification standard, alongside 969 researched vendors. No vendor pays for placement and no vendor has reviewed this page. How this evidence is graded
Choose Hyro if
- Content going stale is your actual failure mode and a self updating graph is the fix.
- Documented coverage is slightly broader and call resolution rate is the metric you own.
- You want the strongest answer engine and already have the rest of the journey handled.
Choose Luma Health if
- Document flow and order management alongside access are in scope.
- HITRUST r2 and SOC 2 Type II are certifications your security review requires.
- Payments as part of the same platform closes a loop you currently hand off.
| At a glance | Hyro | Luma Health |
|---|---|---|
| Category | Healthcare agent | Healthcare agent |
| Entry price | Contact sales | Contact sales |
| Free / trial | None public | None public |
| Pricing confidence | contact only | contact only |
| Feature | H Hyro |
L Luma Health |
|---|---|---|
| Action & orchestration | ||
|
Integrations & Tool Calling Ability to connect agents to real systems through native integrations, OAuth-authenticated actions, custom tools, APIs, webhooks, or MCP-compatible tools. |
Full / Explicit | Full / Explicit |
|
Workflow Orchestration Ability to sequence, branch, retry, route, and combine deterministic workflow nodes with autonomous agent steps. |
Partial | Full / Explicit |
|
Triggers & Channel Coverage How agents wake up and where they work: schedules, webhooks, message events, CRM events, inbox events, chat, email, voice, and collaboration tools. |
Full / Explicit | Full / Explicit |
| Knowledge & context | ||
|
Knowledge Grounding & RAG Ability to ground agent behavior in company data through document ingestion, retrieval, external knowledge APIs, semantic search, or RAG layers. |
Full / Explicit | Partial |
|
Memory & State Persistence Ability to persist context across a run, conversation, workflow, user, team, or longer-term memory layer. |
No / Not documented | No / Not documented |
| Control & trust | ||
|
Human Oversight & Guardrails Approval steps, consent checkpoints, escalation rules, structured guardrails, policy constraints, and pause/resume controls. |
Full / Explicit | Partial |
|
Security, Identity & Governance RBAC, SSO, auditability, encryption, least-privilege tool access, compliance posture, and data handling policy. |
Full / Explicit | Full / Explicit |
|
Observability & Auditability Traces, logs, execution histories, metrics, audit events, and debugging detail for production agent behavior. |
Full / Explicit | Partial |
|
Deployment & Data Residency Deployment modes and options, including SaaS, dedicated cloud, VPC, on-prem, hybrid, local runtime, and self-hosting. |
Partial | Partial |
| Solution readiness | ||
|
Prebuilt Agents, Templates & Packs Ready-made workflows, packaged employees, templates, blueprints, industry solutions, and role-specific agents that reduce time-to-value. |
Full / Explicit | Full / Explicit |
| Platform extensibility | ||
|
Model Flexibility & Routing Ability to work across multiple foundation models, route tasks to different models, or let buyers bring their own providers and keys. |
No / Not documented | Partial |
|
APIs, SDKs & MCP Extensibility Composability layer: stable APIs, SDKs, MCP tool consumption/serving, custom tools, and integration into internal systems. |
No / Not documented | Partial |
|
Testing, Debugging & Optimization Testing, debugging, scoring, retries, fallbacks, quality gates, and optimization loops for improving agent workflows before and after deployment. |
Partial | No / Not documented |
| Specialist automation | ||
|
Browser & Computer Use Browser, desktop, or remote/local computer control for workflows that cannot be handled through stable APIs alone. |
No / Not documented | No / Not documented |
Pricing snapshot
Sourced from the Index pricing dataset · open each vendor's profile for full detail.
| Pricing | H Hyro |
L Luma Health |
|---|---|---|
|
Entry price Lowest public entry point |
Contact sales | Contact sales |
|
Pricing confidence How public the numbers are |
Contact only | Contact only |
|
Billing Primary billing axis |
skills / channels | — |
|
Variable cost Workload / overage exposure |
Medium variable cost | Medium variable cost |
|
Free tier / trial Try before you buy |
No free tier
|
No free tier
|
|
Buying motion Self-serve vs sales call |
Sales call | Sales call |
More comparisons with Hyro or Luma Health
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Not the pairing you were after? These compare a different set of healthcare agents on the same 14 capabilities.